CLINICAL RESEARCH POSTER PRESENTATION ABSTRACTS
Please note: All posters will be displayed in
Salons 10-12.
THURSDAY, 5:30-6:15 PM
Di Duro, Joseph O.
Pain evoked potential processing in manipulative care:
a case series.
Palmer Center for Chiropractic Research joseph.diduro@palmer.edu
OBJECTIVE: To measure pain evoked potentials
(PeVP) in a group of patients as a pilot study to determine if PeVP
processing is influenced by manipulative care.
DESIGN: Two group observational study.
SETTING: Outpatient chiropractic clinic in Italy.
PATIENTS: Ten patients (5 men and 5 women; mean
age 35 years) were examined with PeVP before and after chiropractic
manipulation. These patients were divided into asymptomatic, maintenance
patients (2 male 4 female, mean age 37.5) years and patients suffering
active migraine (3 male, 1 female, mean age 31.3 years). Pain stimulation
was given with a nociceptive specific, surface electrode on the dominant
hand at 1.5 times threshold. The evoked potential was recorded at the
vertex (Cz) before and after the intervention by two trials of 20 stimuli
at 1 Hz, which were averaged and analyzed offline. Intervention: Manual
high-velocity, short-amplitude thrusts to the thoracic and cervical
spine.
MAIN OUTCOME: Change in PeVP (N2-P2) amplitude.
MAIN RESULT: Asymptomatic patients showed a
mean amplitude change of -2.75 milliamps (SD = 2.81, 95% CI -0.22 to
-5.27) while migraine patients showed a smaller change of 0.83 milliamps
(SD = 4.35, 95% CI: -6.10 to 7.75)
CONCLUSION: This observational study provides
data that PeVP processing is altered after chiropractic intervention.
Pain evoked potentials may be a useful tool to investigate the mechanisms
of manipulation induced hypoalgesia in patients.
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