POSTER PRESENTATION ABSTRACTS
Please note: All posters will be displayed in
Salons 10-12.
THURSDAY, 10:15-11:00 AM
Zeggwagh NA, El Amraoui M, Lemhadri A, Eddouks M*.
Anti-hyperglycaemic and hypolipidemic effects of Ocimum
basilicum aqueous extract in diabetic rats.
UFR: PNPE, Faculty of Sciences and Techniques,
Errachidia m.eddouks@caramail.com
*Presenting author
The hypoglycaemic and hypolipidemic effect of the
aqueous extract of Ocimum basilicum (OB) whole plant was investigated
in normal and streptozotocin (STZ) diabetic rats. After single oral
administration OB significantly reduces blood glucose levels in normal
(p<0.01) and diabetic rats (p<0.001). After 15 days of repeated oral
administration, OB produce potent reduction on blood glucose levels
(p<0.001) in diabetic rats and less reduction in normal rats (p<0.05).
Total plasma cholesterol and triglycerides levels were significantly
reduced after repeated oral administration in diabetic rats (p<0.001)
and (p<0.05) respectively. However, no change was observed in total
plasma cholesterol and triglycerides levels in normal rats after both
single and repeated oral administration. In addition, plasma insulin
levels and body weight remain unchanged over 15 days of oral administration
in normal and diabetic rats. We conclude that the aqueous extract of
OB exhibits a potent anti-hyperglycaemic and hypoglycaemic activities
in diabetic rats without affecting basal plasma insulin concentration.
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