DISCUSSION Thursday, May 25, 2:00-4:30


Methodological Challenges in Whole Systems Research

Speakers: Cheryl Ritenbaugh, PhD, MPH, Charles Elder, MD, MPH, Vinjar Fønnebø, MD, Marja Verhoef, PhD, Mikel Aickin, PhD, Richard Hammerschlag, PhD, Iris Bell, MD, PhD, George Lewith, DM

While most CAM research has focused on single modal interventions, CAM practitioners commonly prescribe holistic, multimodality therapies, operating from paradigms that may assume non-linear, non-local approaches to health/illness. NCCAM's 2005-2009 Strategic Plan emphasizes the importance of conducting Whole Systems Research (WSR). Specifically, NCCAM seeks to acquire a richer understanding of CAM whole medical systems and how they operate, document the benefits of some CAM whole medical system treatments for selected health conditions, and elucidate mechanisms underlying successful multimodal treatments used in CAM whole medical systems. Achievement of these goals within a WSR paradigm presents multiple challenges to current methodological approaches.

This session will provide an opportunity for dialogue about these challenges and exploration of diverse perspectives about methodologies appropriate for WSR. The first half of the session will highlight general themes salient to whole system studies. Panelists will review key differences between allopathic and CAM care, emphasizing the nature, and importance, of nonspecific treatment effects. Methodologic issues specific to WSR will be detailed from both quantitative and qualitative vantage points with a focus on model validity. WSR must consider unique dynamics such as the patient practitioner interaction and individually tailored treatments, and quantitative strategies for coping with these challenges will be elucidated, along with novel approaches to study design. Qualitative approaches to capturing patient centered outcomes will likewise be reviewed, emphasizing the role of patient expectations and beliefs in influencing outcomes, and strategies for capturing and describing that dynamic. Finally, the central role of the practitioner's perspective will be examined, as it may impact both conventional outcomes and nonspecific effects.

The second part of the session will review applications of these issues within specific CAM whole systems of care, emphasizing issues of special relevance to each system. Panelists will discuss WSR as applied to homeopathy, with a special focus on issues related to practitioner perspective. Application of WSR within Traditional Chinese Medicine will likewise be detailed, including approaches to managing the dynamic of dual CAM/allopathic diagnoses. Finally, a panelist will consider issues related to integrated medicine practitioners, e.g. what special considerations are introduced where the practitioner may have competence in both allopathic care and a CAM system?

Woven throughout the discussion will be unique and often divergent perspectives brought to these issues by both panelists and attendees of various national and professional backgrounds. This discussion will encourage progress and insight toward designing and conducting rigorous scientific WSR in keeping with the goals presented by NCCAM.

 

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